Lipid Profile in Pediatric Patients with Hypovitaminosis D

Abstract

Introduction: Proactive diagnosis of lipid status disorders can significantly contribute to the therapeutic approach of patients with hypovitaminosis D and ensure a better quality of life, if the importance of the condition is recognised as early as in the pediatric age. 

Aim: The aim of the research was to examine the existence of a correlation between changes in lipid status and the degree of vitamin D deficiency within a pediatric group of patients with an existing diagnosis of hypovitaminosis D.

 Materials and Methods: The entire research included 32 patients, 10 boys and 22 girls, treated at the Institute for Health Care of Children and Youth of Vojvodina in 2024. Laboratory parameters considered included: TAG, Chol, HDL, LDL, VLDL, vitamin D levels, BMI, gender, and age. The interpretation of the results was performed using the ANOVA and Kruskal-Wallis statistical methods. 

Results: With the size of the studied group and interindividual differences taken into account, the study did not show statistically significant differences in lipid status depending on the level of vitamin D, nor in terms of the studied parameters (BMI, gender, and age). 

Conclusion: We can claim that there is a correlation, but not causation, when it comes to the influence of vitamin D levels on the lipid profile in the pediatric population of patients diagnosed with hypovitaminosis D. Therefore, lipid status together with vitamin D levels may be of clinical importance as preventable cardiometabolic risk factors in the pathogenesis of complications resulting from hypovitaminosis D.